If you draw a vacuum on the chamber and apply a high voltage to both ends, then a blueish purple glowing line forms. The simplest cathode ray tube is a sealed glass chamber that has electrodes at either end and a port to be able to draw a vacuum from. So many of you may be wondering now, how does a cathode ray tube work?Ī cathode ray tube consists of a ray going from the cathode to the anode, and it is made up of electrons. They are still used widely today as oscilloscope screens, but these cathode ray tubes as screens are a little bit more complicated than the simple cathode ray tube that we are going to be building in this instructable. These tubes have been used as television screens for all of the 20th century and for the early part of the 21st century. In fact, the first one was built in 1897 by scientist Ferdinand Braun. The video below compliments this instructable with a visual demonstration of this Cathode Ray Tube in action.ĬRT's have been around for a long time. This piece of test equipment that I will show you how to build can be used as an awesome scientific demonstration for any physics and chemistry class, or it can be used just as a way to confirm a long standing scientific principal. I'll explain how it proves this theory later in this instructable. This line not only looks cool, but it can be used to prove a scientific theory electrons are a subatomic unit with a negative charge. You can manipulate and bend this stream of electrons with a magnet. This is a stream of electrons that looks like a brilliant blue-purple line of plasma. When there is a vacuum drawn and a high voltage across the two electrodes, a cathode ray forms. A cathode ray tube, or CRT, is a glass tube with electrodes on either end. Luckily, there is a device that will let you. Electrons: they are all around us, but we cannot really see or interact with them.
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Significance of TP53 Mutation in Wilms Tumors with Diffuse Anaplasia: A Report from the.Genomic Data Commons by National Cancer Institute.TARGET data matrix by National Cancer Institute.TARGET projects provide comprehensive molecular characterization to determine the genetic changes that drive the initiation and progression of childhood cancers.The dataset contains open Clinical Supplement, Biospecimen. The goal of the effort is to accelerate molecular discoveries that drive the initiation and progression of hard-to-treat childhood cancers and facilitate rapid translation of those findings into the clinic. Therapeutically Applicable Research to Generate Effective Treatments (TARGET) is the collaborative effort of a large, diverse consortium of extramural and NCI investigators. Therapeutically Applicable Research to Generate Effective Treatments (TARGET) SARS-CoV-2 spike RBD bound to monoclonal antibody S2H97 (623.7 us) by The Chodera lab at the Memorial Sloan Kettering Cancer Center.SARS-CoV-2 spike RBD with N501Y mutation bound to human ACE2 (953.7 µs) by The Chodera lab at the Memorial Sloan Kettering Cancer Center.SARS-CoV-2 spike RBD with P337A mutation bound to monoclonal antibody S309 (907.0 µs) by The Chodera lab at the Memorial Sloan Kettering Cancer Center.SARS-CoV-2 spike protein dataset: A 1.2 ms dataset of the SARS-CoV-2 spike protein in search of cryptic pockets by The Bowman lab at Washington University in St.SARS-CoV-2 spike RBD (with glycosylation) (1.8 ms) by The Chodera lab at the Memorial Sloan Kettering Cancer Center.The complete index of all datasets can be found here. In addition to working directly with experimental collaborators and rapidly sharing new research findings through preprint servers, has joined other researchers in committing to rapidly share all COVID-19 research data, and has joined forces with AWS and the Molecular Sciences Software Institute (MolSSI) to share datasets of unprecedented side through the AWS Open Data Registry, indexing these massive datasets via the MolSSI COVID-19 Molecular Structure and Therapeutics Hub. More information about COVID-19 research activities at the COVID-19 page. In the process, it created the world's first exascale distributed computing resource, enabling it to generate valuable scientific datasets of unprecedented size. During the COVID-19 epidemic, focused its resources on understanding the vulnerabilities in SARS-CoV-2, the virus that causes COVID-19 disease, and working closely with a number of experimental collaborators to accelerate progress toward effective therapies for treating COVID-19 and ending the pandemic. Run by the Consortium, a worldwide network of research laboratories focusing on a variety of different diseases, seeks to address problems in human health on a scale that is infeasible by another other means, sharing the results of these large-scale studies with the research community through peer-reviewed publications and publicly shared datasets. Hoadley, Christina Yau, et al.Īlchemical free energy calculations biomolecular modeling coronavirus COVID-19 foldingathome health life sciences molecular dynamics protein SARS-CoV-2 simulations structural is a massively distributed computing project that uses biomolecular simulations to investigate the molecular origins of disease and accelerate the discovery of new therapies. Cell-of-Origin Patterns Dominate the Molecular Classification of 10,000 Tumors from 33 Typesīy Katherine A.An Integrated TCGA Pan-Cancer Clinical Data Resource to Drive High-Quality Survival Outcomeīy Jianfang Liu, Tara Lichtenberg, et al.Pan-Cancer Analysis of lncRNA Regulation Supports Their Targeting of Cancer Genes in Eachīy Hua-Sheng Chiu, Sonal Somvanshi, et al.Genomic, Pathway Network, and Immunologic Features Distinguishing Squamous Carcinomas by Joshua D.The dataset contains open Clinical Supplement, Biospecimen Supplement, RNA-Seq Gene Expression Quantification, miRNA-Seq Isoform Expression Quantificati. TCGA has analyzed matched tumor and normal tissues from 11,000 patients, allowing for the comprehensive characterization of 33 cancer types and subtypes, including 10 rare cancers. The Cancer Genome Atlas (TCGA), a collaboration between the National Cancer Institute (NCI) and National Human Genome Research Institute (NHGRI), aims to generate comprehensive, multi-dimensional maps of the key genomic changes in major types and subtypes of cancer. Cancer genomic life sciences STRIDES whole genome sequencing E-file fees do not apply to NY state returns.Īdditional disclaimer for business e-files: State e-file for business returns only available in CA, CT, MI, NY, VA, WI Most personal state programs available in January release dates vary by state.
Or additional protectors can be added to the volume first. Encrypting data volumes can be done using the base command: If verify if a TPM protector is available, the list of protectors available for a volume can be listed by running the following command: manage-bde.exe -protectors -get ĭata volumes use the same syntax for encryption as operating system volumes but they don't require protectors for the operation to complete. The above command encrypts the drive using the TPM as the default protector. To enable BitLocker on a computer with a TPM without defining any protectors, enter the following command: manage-bde.exe -on C: On computers with a TPM, it's possible to encrypt the operating system volume without defining any protectors using manage-bde.exe. With the protectors enabled on the volume, BitLocker can then be turned on. The above command will require the password protector to be entered and confirmed before adding them to the volume. To add the protectors, enter the following command: manage-bde.exe -protectors -add C: -pw -sid In this scenario, the protectors are added first. manage-bde.exe -protectors -add C: -startupkey E:Īfter the encryption is completed, the USB startup key must be inserted before the operating system can be started.Īn alternative to the startup key protector on non-TPM hardware is to use a password and an ADaccountorgroup protector to protect the operating system volume. Once the commands are run, it will prompt to reboot the computer to complete the encryption process. In this example, the drive letter E represents the USB drive. When BitLocker is enabled for the operating system volume, BitLocker will need to access the USB flash drive to obtain the encryption key. Before beginning the encryption process, the startup key needed for BitLocker must be created and saved to a USB drive. The following example illustrates enabling BitLocker on a computer without a TPM chip. This command returns the volumes on the target, current encryption status, encryption method, and volume type (operating system or data) for each volume: Use the following command to determine volume status: manage-bde.exe -status It's recommended to add at least one primary protector plus a recovery protector to an operating system volume.Ī good practice when using manage-bde.exe is to determine the volume status on the target system. However, many environments require more secure protectors such as passwords or PIN and expect information recovery with a recovery key. In general, using only the manage-bde.exe -on command will encrypt the operating system volume with a TPM-only protector and no recovery key. Listed below are examples of basic valid commands for operating system volumes. Using manage-bde with operating system volumes The following sections provide examples of common usage scenarios for manage-bde. A volume encrypted in this manner still requires user interaction to turn on BitLocker protection, even though the command successfully completed because an authentication method needs to be added to the volume for it to be fully protected. For example, using just the manage-bde.exe -on command on a data volume will fully encrypt the volume without any authenticating protectors. Manage-bde includes fewer default settings and requires greater customization for configuring BitLocker. For a complete list of the manage-bde.exe options, see the Manage-bde command-line reference. Manage-bde offers additional options not displayed in the BitLocker control panel. Manage-bde is a command-line tool that can be used for scripting BitLocker operations.
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Note: Most larger products are delivered curbside/outside via a Freight company. If your item(s) are available for immediate shipment (on business days) we will process the charges and submit the order to the destination. Due to the larger size of our products we do not offer express shipping options. Products usually ship out fast within 24-72 hours on business days via UPS, Fedex, or Freight Delivery depending on your items size. Within a few years even the original went into severe decline but by then the Hunan/Szechuan rage in Chicago was well underway.Ĭynthia wrote:While I didn't eat egg foo yung or chow mein growing up, we ate a lot of Cantonese food (especially from Bob Chinn's first venture, House of Chan in Wilmette). The restaurant became very popular and many imitators soon appeared (notably one on N Michigan, whose owners had bought the name). This is the first restaurant I recall that warned diners with red underlining. They served the by-then-common hot and sour soup and sizzling rice dishes but introduced dishes such as willow beef with a serious chili heat. House of Hunan, on the second floor at 3150 N Lincoln, was the first to popularize the spicy fare of Hunan and Szechuan. In 1974 another influential Chinese restaurant opened in Chicago. Many of these restaurants served a roughly similar hodgepodge of a menu characterized by hot and sour soup, sizzling rice soup, moo shu pork, Peking duck and glazed bananas for dessert (often dumped from a pan into a bowl of ice water). In the early 1970s other "Mandarin" restaurants opened in quick succession: Tien Tsin in Rogers Park, Man Dar Inn in Chinatown (run by some Dragon Inn founders), the upscale Mandarin House and many others. By the early 1970s he was involved in such restaurants as Cathay Mandarin and Peter Lo's (first in Rogers Park, later on N Lincoln). In 1967 Peter Lo left the Dragon Inn to open his own place, the Chinese Tea House on the northwest side. Within ten years they expanded to the north side (Dragon Seed in the Belmont Stratford) and north suburbs (Dragon Inn North). Dragon Inn was perhaps the first area restaurant to serve such then-exotic dishes as hot and sour soup and moo shu pork-a significant departure from Chicago's steady diet of chow mein and egg foo yung. In 1964 an important restaurant opened in a shopping center in the far-south suburb of Glenwood. Dragon Inn in the southern suburbs was the first in the Chicago area in the 1960s although another Mandarin restaurant opened in West Lafayette, IN about the same time and may have been slightly earlier. In the Chicago area Peter Lo's and various restaurants with Dragon in the name were examples. These restaurants typically derived from academically connected people from Taiwan with Kuomintang (Chiang Kai-shek's party) origins on the mainland before the Communists took over. Ekreider wrote:The dishes in OP were common at Mandarin restaurants in the 1970s. Strong winds and hail were reported across Louisiana, Mississippi, Alabama and Georgia on Sunday, with forecasters expecting heavy rain and the potential for flash flooding into Monday. More bad weather is expected in the Southeast "I'm not going to be none of that, because I lost everything, but I gained another day above ground. I'm not going to be depressed," Berry said. She managed to get to a shelter before the tornado hit, but her home was wiped away. In the rural True Light community nearby, Kimberly Berry was among the survivors. The roof of Rolling Fork's city hall was ripped off, the business district was badly damaged and the tornado even toppled the town's water tower. One of the hardest hit areas was Rolling Fork, a predominantly Black town of about 2,000 residents, which Reeves described as "ground zero" for the storm. NPR Kimberly Berry's home was destroyed in the rural community of True Light. local time roughly an hour's drive from Jackson lasted for more than an hour and traversed roughly 170 miles. The powerful twister that began Friday night around 8 p.m. People are also handing out food, bottles of water and clothing to those in need. Rescuers are sifting through rubble to ensure no other survivors are trapped, while utility workers have been racing to restore power. Now, survivors are returning to their homes to look for important items, such as car keys and medicine. "Incredibly inspired by how Mississippians have come together in this tragic moment," he said. On Saturday, Reeves declared a state of emergency and shared images on social media of rescue workers and others helping in the recovery effort throughout the day. Emergency workers were also preparing for more severe weather, with thunderstorms, hail and additional tornadoes in the forecast. Tate Reeves and other officials to assess the damage. Secretary of Homeland Security Alejandro Mayorkas traveled to Mississippi on Sunday and met with Gov. Here is a look at some of the tornado damage in Rolling Fork, Mississippi from the storm on March 24, 2023. One of those early upgrades, which you should pick up as soon as possible, is a Keepsake Collection at the end of every level. In Hades, you’ll collect Gems on your travels, which you can spend with the House of Hades Contractors for some sweet upgrades. Change your Keepsakes often You can get Keepsakes from all these Gods and much more Image: Supergiant Games via Polygon Keep one or two on you, but if it’s really stacking up, consider trading it for something that will impact your gameplay a little earlier, like Titan’s Blood. You won’t use the Ambrosia for a long time. Hold onto your Titan’s Blood and Diamonds, as they can offer you some pretty massive gameplay upgrades once you can actually spend them. Ambrosia deepens your friendships with characters after you’ve already given them a ton of NectarĪs you progress, you’ll unlock an exchange shop in the lounge of the House of Hades.Diamonds help you improve the House of Hades.Though you won’t use many of them until later in the run, these are all useful items. The three big materials are: Diamonds, Titan Blood, and Ambrosia. When you defeat a boss for the first time with any of the game’s six weapons, you’ll get a hard-to-find material. Don’t be too precious with your materials Even if you’re not much of a story person, it’s worth giving Hades’ characters a shot before you just button mash through the dialogue. It’ll make a difference.Īlso the developers at Supergiant are well-known for their narrative and writing. Before you head back into hell, chat up your pals a bit. These are the ones with something new to say. Some have exclamation marks over their heads. You can do this with Nectar, yes, but also just by talking to people.Įach time you return to the House of Hades, you’ll find a variety of NPCs. But you’ll need to keep your relationship up with characters if you want to unlock some late-game items. Usually, the story is pretty separate from the gameplay. Unlike most roguelikes, Hades has a big focus on narrative. Who knows, you may find a combo you never expected. You’ll eventually get through bosses and areas, but early on, pick weapons and Boons you normally wouldn’t just to get an idea of the potential in Hades. Focus more on experimentation and less on kicking ass. You’ll lose quite a few times before you ever finish the final boss. In those early hours, you’ll still be figuring out how everything works while you play, and every new Boon and boss will be a surprise. Part of the reason you should pick up Keys early is so you can access tons of abilities and weapons at the beginning. Sisyphus appears in Tartarus, Eurydice appears in Asphodel, Patroclus appears in Elysium, and Thanatos is a random event in any area once you’ve met him in Elysium. You’ll know an event room by the door preview, which features a gray rock with an exclamation point on it. Since running into them is random, keep some Nectar on you, just in case you find them. We’ve gone five or more runs without seeing Patroclus, Eurydice, Thanatos, and Sisyphus. Keep one Nectar in your pocket, at least until you have all the Keepsakes.Ĭertain Hades characters only appear at random. Hades guide: Nectar Keep some Nectar for Patroclus, Eurydice, Thanatos, and Sisyphus Image: Supergiant Games via Polygon It’s a fun way to spice up your gameplay each run. Focus on getting all of the weapons in Hades first. You’ll have plenty of runs to go for the win, so keep one eye on the future and nab those Keys early. Keys unlock new weapons back in the House of Hades and new skills for you to pick from at the Mirror of Night. When you’re starting out, focus on Keys (they look like keys, so they’re pretty tough to miss). But others, like Darkness and Keys, let you upgrade Zagreus for your next foray into the Underworld. Some of these rewards, like Boons, benefit the run you’re on. When you finish a battle in the underworld, you’ll get a glimpse at the reward for an upcoming room displayed on the door that leads out. Focus on Keys first Image: Supergiant Games via Polygon Here are nine tips to help you through your first few hours of Hades. Part of Hades’ charm is your discovery of how the game works, but there are still several things to keep in mind as you start your journey. There’s a lot to take in, a ton of decisions to make, and the game purposefully doesn’t give you all the information you need. When you first jump into Hades, it can be pretty overwhelming. Hades is an incredible, run-based video game set in the Greek underworld. all volumes not used by at least one container all networks not used by at least one container Hello-world latest 46331d942d63 7 weeks ago 9.14kB Furthermore you can do install distributions like Alpine and run them: $ docker pull alpineīin dev etc home lib media mnt opt proc root run sbin srv sys tmp usr varĪlpine latest 3fb3c9af89a9 5 weeks ago 5.32MB You'll then notice that after you successfully set it up and run docker run hello-world that it does work. The key, however, is to just use Docker itself with something like a tutorial from here: This tries to run a nested virtualization scenario and Apple does not have this instruction set available on the M1 series of Apple Silicon devices. The catch or hang up that people are hitting is when they try to use "Docker Desktop" on Ubuntu (instead of directly on macOS). There was a question below about whether or not Docker can work with Ubuntu 22.04 on Apple Silicon. Expand Parallels Desktop.app/Contents/Resources/Tools/.Navigate to /Applications/ and change to List view.Note: initially I installed Parallels Tools before installing the graphical user interface, but if you install it after the installation of ubuntu-desktop or even kde-standard/full/whatever then copy paste, etc.Use ISO: mount Parallels ARM64 tools ISO and install: Menubar → Actions → Install Parallels Tools.
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